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    Β2 adrenergic agonist, clenbuterol, enhances working memory performance in aging animals – PMC Journal List HHS Author Manuscripts PMC3154024 Neurobiol Aging. Author manuscript; available in PMC 2011 Aug 10. Published in final edited form as: Neurobiol Aging. 2008 Jul; 29 (7): 1060–1069. Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. Some doctors even recommend taking the K with the clenbuterol if you have asthma since it keeps working for longer and clears out the beta two receptors. Clenbuterol, a beta 2 -adrenergic receptor (β 2 -AR) selective agonist, has been shown to decrease body fat in animals and can induce apoptosis in adipose tissue in mice. We hypothesized that direct actions of a β-adrenergic receptor agonist on adipocytes could trigger the observed apoptotic effect. Abstract Beta-2 agonists are drugs that selectively mimic the actions of the endogenous catecholamines epinephrine and norepinephrine. As pharmaceuticals, their major role is to reduce signs and symptoms of asthma and chronic obstructive pulmonary disease by bronchodilation, allowing the patient to breathe more easily. It is well known that Clenbuterol use results in rapid down-regulation of beta 2 receptors. This is due to the powerful stimulatory effect of the drug. It is therefore pointless to use Clen for long periods without a break. Some believe that a 2 day on, 2 day off dosing schedule will allow adequate potential for receptor up-regulation 
     
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